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Microchip Method in IVF Treatment
Laboratory

Microchip Method in IVF Treatment

7 November 20254 min readNicosia IVF Center

An advanced sperm selection technique that improves fertilization and embryo development by selecting healthy sperm with minimal DNA damage.

What is the microchip?

The microchip method is an advanced sperm selection technique used in IVF treatment. Its purpose is to improve fertilization and embryo development by selecting higher-quality, healthy sperm with minimal DNA damage. The microchip is a microfluidic chip with specialized channels; sperm pass over its surface through a natural selection process, allowing the selection of the best-moving sperm with healthy membranes and intact DNA.

Benefits of the microchip in IVF

Selects sperm with low DNA damage.
Increases fertilization rates.
Improves embryo quality.
Enhances pregnancy and live birth rates.
May reduce miscarriage risk, as shown in some studies.

Recommended especially for

History of recurrent miscarriage
Previous failed IVF attempts
Male factor issues such as sperm DNA damage or abnormal morphology

How much does it increase success rates?

Scientific studies vary, but on average the microchip can increase pregnancy rates by 10–20%. This improvement is particularly notable in couples with low sperm quality.

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